Comparative evaluation of Nardostachys jatamansi and Mucuna pruriens as neuroprotective in Parkinson's disease
نویسندگان
چکیده
منابع مشابه
Mucuna pruriens in Parkinson disease
OBJECTIVE To investigate whether Mucuna pruriens (MP), a levodopa-containing leguminous plant growing in all tropical areas worldwide, may be used as alternative source of levodopa for indigent individuals with Parkinson disease (PD) who cannot afford long-term therapy with marketed levodopa preparations. METHODS We investigated efficacy and safety of single-dose intake of MP powder from roas...
متن کاملNeuroprotective Effects of Mucuna pruriens Against Stress-Induced Oxidative Damage
Stress is known to alter the cellular homeostasis by oxidative damage in brain which in turn involves in various forms of neurotoxicity including neuronal death. The seed powder of the leguminous plant, Mucuna pruriens (MP) has long been used in traditional Ayurvedic Indian medicine for various neurological diseases including Parkinsonism. The neuroprotective and neurorestorative effect of MP w...
متن کاملComparative evaluation of extract of Bacopa monnieri and Mucuna pruriens as neuroprotectant in MPTP model of Parkinson’s disease
Parkinson’s disease (PD) results primarily from the death of dopaminergic neurons in substantia nigra. Treatment of PD has been shifted recently towards herbal medicines. Bacopa monnieri (L.) Wettst. (BM) and Mucuna pruriens (L.) DC (MP) are traditional herbal plants known to have neuroprotective effects due to the presence of bacosides in whole plant extract of Bacopa monnieri (BME) and L-DOPA...
متن کاملStress modulating antioxidant effect of Nardostachys jatamansi.
The rhizomes of Nardostachysjatamansi, the plant commonly known as Jatamansi have been described in Ayurveda for their soothing and sedative action on the central nervous system. In the present study, the anti-stress effect of hydroethanolic extract (70%) of N. jatamansi (NJE) was evaluated in reference to its antioxidant property. Wistar rats were divided into four groups: naive, stressed, and...
متن کاملLevodopa in Mucuna pruriens and its degradation
Mucuna pruriens is the best known natural source of L-dopa, the gold standard for treatment of Parkinsonism. M. pruriens varieties are protein rich supplements, and are used as food and fodder worldwide. Here, we report L-dopa contents in seeds of fifty six accessions of four M. pruriens varieties, M. pruriens var. pruriens, M. pruriens var. hirsuta, M. pruriens var. utilis and M. pruriens var....
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ژورنال
عنوان ژورنال: Asian Journal of Pharmacy and Pharmacology
سال: 2020
ISSN: 2455-2674
DOI: 10.31024/ajpp.2020.6.3.9